TCAF1 Promotes TRPV2-mediated Ca2+ Release in Response to Cytosolic DNA to Protect Stressed Replication Forks
Nature Communications 2024, accepted
Kong L, Cheng C, Cheruiyot A, Yuan J, Yang Y, Hwang S, Foust D, Tsao N, Wilkerson E, Mosammaparast N, Major MB, Piston DW, Li S and You Z
Cytosolic DNA Sensing by cGAS/STING Promotes TRPV2-mediated Ca2+ Release to Protect Stressed Replication Forks
Molecular Cell 2023; 83:556-573.
Li S, Kong L, Meng Y, Cheng C, Lemacon DS, Yang Z, Tan K, Cheruiyot A, Lu Z and You Z.
CaMKK2 and CHK1 phosphorylate human STN1 in response to replication stress to protect stalled forks from aberrant resection
Nature Communications 2023; 14: 7882, doi.org/10.1038/s41467-023-43685-2
Jaiswal RK, Lei KH, Chastain M, Wang Y, Shiva O, Li S, You Z, Chi P, Chai W
The ATM-E6AP-MASTL axis mediates DNA damage checkpoint recovery
eLife 2023; https://doi.org/10.7554/eLife.86976.1
Li Y, Wang F, Li X, Wang L, Yang Z, You Z and Peng A.
Clinical evidence for a role of E2F1-induced replication stress in modulating tumor mutational burden and immune microenvironment
DNA Repair 2023; doi.org/10.1016/j.dnarep.2023.103531
Tan K, Song Y, Xu M and You Z.
Context-dependent Pro- and Anti-resection Roles of ZKSCAN3 in the Regulation of Fork Processing during Replication Stress
Journal of Biology Chemistry 2022; 298:102215.
Yang Z, Lemacon DS, Li S, Cheruiyot A, Kong L, Tan K, Cheng C, Turkay E, He D, You Z.
Nonsense-mediated RNA Decay is a Unique Vulnerability of Cancer Cells Harboring SF3B1 or U2AF1 Mutations
Cancer Research 2021; 81:4499-4513
Cheruiyot A, Li S, Nonavinkere SS, Ahmed T, Chen Y, Lemacon DS, Li Y, Tang Z, Wadugu BA, Warner WA, Pruett-Miller SM, Obeng EA, Lin DC, He D, Xiao F, Bailis JM, Walter MJ, You Z
Phospho-Ser784-VCP is Required for DNA Damage Response and is Associated with Poor Prognosis of Chemotherapy-Treated Breast Cancer
Cell Reports 2020; 31: 107745.
Zhu C, Rogers A, Asleh K, Won J, Gao D, Leung S, Li S, Vij KR, Zhu J, Held J, You Z, Nielsen TO and Shao J
Ca2+-stimulated AMPK-dependent Phosphorylation of Exo1 Protects Stressed Replication Forks from Aberrant Resection
Molecular Cell 2019; 74: 1123-1137.
Li S, Lavagnino Z, Lemacon D, Kong L, Ustione A, Ng X, Zhang Y, Wang Y, Zheng B, Piwnica-Worms H, Vindigni A, Piston DW and You Z
Repair of Protein-linked DNA Double-strand Breaks: Using the Adenovirus Genome as a Model Substrate in Cell-based Assays
DNA Repair 2018; 74:80-90.
Lamarche BJ, Orazio NI, Goben B, Meisenhelder J, You Z, Weitzman MD, Hunter T
Compound C Inhibits Nonsense-mediated RNA Decay Independently of AMPK
PLoS One 2018; 13: e0204978.
Cheruiyot A*, Li S*, Nickless A, Roth R, Fitzpatrick JAJ and You Z
Studying Nonsense-mediated mRNA Decay in Mammalian Cells Using a Multicolored Bioluminescence-based Reporter System
Methods in Molecular Biology 2018; 1720: 231-224.
Nikcless A and You Z
Dna2 Initiates Resection at Clean DNA Double-strand Breaks
Nucleic Acids Research 2017; 45(20):11766-11781.
Paudyal SC, Li S, Yan H, Hunter T and You Z
Mre11 and Exo1 Nucleases Degrade Reverse Forks and Elicit Mus81-dependent Fork Rescue in BRCA2-deficient Cells
Nature Communications 2017; 8:860-872.
Lemacon D, Jackson J, Quinet A, Bricker JR, Li S, Yazinski S, You Z, Ira G, Zou L, Mosammaparast N, Vindigni A
p38 MAPK Inhibits Nonsense-mediated RNA Decay in Response to Persistent DNA Damage in Non-cycling Cells
Journal of Biological Chemistry 2017; 292: 15266-15276.
Nickless A, Cheruiyot A, Flanagan KC, Piwnica-Worms D, Stewart SA and You Z
Control of Gene Expression through the Nonsense-mediated RNA Decay Pathway
Cell & Bioscience 2017; 7:26.
Nickless A, Bailis JM and You Z
Sharpening the Ends for Repair: Mechanisms and Regulation of DNA Resection
Acta Biochim Biophys Sin 2016; 48(7):647-657.
Paudyal SC and You Z
USP51 Deubiquitylates H2AK13,15ub and Regulates DNA Damage Response
Genes and Development 2016; 30(8): 946-959.
Wang Z, Zhang H, Liu J, Cheruiyot A, Lee JH, Ordog T, Lou Z, You Z and Zhang Z
A Cell Cycle-dependent BRCA1-UHRF1 Cascade Regulates DNA Double-strand Break Repair Pathway Choice
Nature Communications 2016; 7: 10201.
Zhang H, Liu H, Chen Y, Yang X, Wang P, Liu T, Geng M, Qin B, Correia C, Lee S, Kim J, Spark M, Nair AA, Evans DL, Kalari KR, Zhang P, Wang L, You Z, Kaufmann SH, Lou Z and Pei H
Poly(ADP-ribose)-binding Promotes Exo1 Damage Recruitment and Inhibits Its Nuclease Activities
DNA Repair 2015; 35: 106-115.
Cheruiyot A*, Paudyal SC*, Kim IK*, Sparks M, Ellenberger T, Piwnica-Worms H and You Z (equal contributors)